Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of TGF-β in a mouse model of breast cancer.

Transforming growth factor-βs (TGF-βs) play a dual role in carcinogenesis, functioning as tumor suppressors early in the process, and then switching to act as pro-metastatic factors in late-stage disease. We have previously shown that high molecular weight TGF-β antagonists can suppress metastasis w...

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Autori principali: Nam, Jeong-Seok, Suchar, Adam M., Kang, Mi-Jin, Stuelten, Christina H., Tang, Binwu, Michalowska, Aleksandra M., Fisher, Larry W., Fedarko, Neal S., Jain, Alka, Pinkas, Jan, Lonning, Scott, Wakefield, Lalage M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1528715/
https://ncbi.nlm.nih.gov/pubmed/16778210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-0068
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