Low pH-induced changes in Pseudomonas exotoxin and its domains: increased binding of Triton X-114.

Pseudomonas exotoxin (PE), which is composed of three structural domains, is a 66-kilodalton protein secreted by P. aeruginosa that is cytotoxic for mammalian cells. After binding to cell surface receptors and internalization into low-pH endocytic vesicles, PE or an active fragment kills mammalian c...

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Vydáno v:	Infect Immun
Hlavní autoři:	Idziorek, T, FitzGerald, D, Pastan, I
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2108931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.5.1415-1420.1990
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