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Low pH-induced changes in Pseudomonas exotoxin and its domains: increased binding of Triton X-114.
Pseudomonas exotoxin (PE), which is composed of three structural domains, is a 66-kilodalton protein secreted by P. aeruginosa that is cytotoxic for mammalian cells. After binding to cell surface receptors and internalization into low-pH endocytic vesicles, PE or an active fragment kills mammalian c...
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| Publicado en: | Infect Immun |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1990
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2108931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.5.1415-1420.1990 |
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