Circulating Biomarkers of Cell Death after treatment with the BH-3 mimetic ABT-737 in a Pre-clinical Model of Small Cell Lung Cancer

PURPOSE: This study evaluated epithelial cell death ELISAs that measure circulating Cytokeratin-18 (CK18) in mice bearing Small Cell Lung Cancer (SCLC) xenografts treated with a pro-apoptotic dose of the BH-3 mimetic ABT-737. EXPERIMENTAL DESIGN: H146 tumour bearing and non bearing SCID/bg mice were...

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Detaylı Bibliyografya
Asıl Yazarlar: Micha, Dimitra, Cummings, Jeff, Shoemaker, Alex, Elmore, Steven, Foster, Kelly, Greaves, Martin, Ward, Tim, Rosenberg, Saul, Dive, Caroline, Simpson, Kathryn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586103/
https://ncbi.nlm.nih.gov/pubmed/19010845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0111
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