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Circulating Biomarkers of Cell Death after treatment with the BH-3 mimetic ABT-737 in a Pre-clinical Model of Small Cell Lung Cancer
PURPOSE: This study evaluated epithelial cell death ELISAs that measure circulating Cytokeratin-18 (CK18) in mice bearing Small Cell Lung Cancer (SCLC) xenografts treated with a pro-apoptotic dose of the BH-3 mimetic ABT-737. EXPERIMENTAL DESIGN: H146 tumour bearing and non bearing SCID/bg mice were...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586103/ https://ncbi.nlm.nih.gov/pubmed/19010845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0111 |
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