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Out of breath: GM-CSFRα mutations disrupt surfactant homeostasis
Pulmonary alveolar proteinosis (PAP) is a rare disorder in which surfactant homeostasis in the lung is impaired, causing respiratory distress and, in severe cases, respiratory failure. Most cases of PAP are associated with the formation of autoantibodies against the cytokine granulocyte/macrophage c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585835/ https://ncbi.nlm.nih.gov/pubmed/19015311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082378 |
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