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Gene therapy for Primary Immunodeficiencies: looking ahead, towards gene correction

Allogeneic hematopoietic stem cell transplantation is the treatment of choice for severe primary immunodeficiencies (PIDs). For patients lacking an HLA-identical donor, gene therapy is an attractive therapeutic option. Approaches based on insertion of a functional gene using viral vectors have provi...

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Detalhes bibliográficos
Main Authors: Pessach, Itai M., Notarangelo, Luigi D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105180/
https://ncbi.nlm.nih.gov/pubmed/21440291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.02.027
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