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Targeted Strategies Directed at the Molecular Defect: Towards Precision Medicine for Select Primary Immunodeficiency Disorders

Primary immunodeficiency disorders (PIDs) represent a range of genetically determined diseases that typically have increased susceptibility to infections and in many also have evidence of immune dysregulation that often presents as autoimmunity. Most recently, the concept of gain of function (GOF) m...

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Bibliographische Detailangaben
Veröffentlicht in:J Allergy Clin Immunol
Hauptverfasser: Notarangelo, Luigi D., Fleisher, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369241/
https://ncbi.nlm.nih.gov/pubmed/28270363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.01.004
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