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Diastereoselection in the Formation of Spirocyclic Oxindoles by the Intramolecular Heck Reaction

Diastereoselective double Heck cyclizations of cyclohexene diamides 1 and 3 form contiguous quaternary stereocenters, with diastereoselection being controlled by the trans diol-protecting group. In this, the first in a series of two papers, the origin of diastereoselection in the first ring closure...

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Autors principals: Overman, Larry E., Watson, Donald A.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585599/
https://ncbi.nlm.nih.gov/pubmed/16555809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo052335a
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