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An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
We have developed a nanoparticle formulation [liposomes-protamine-hyaluronic acid nanoparticle (LPH-NP)] for systemically delivering siRNA into the tumor. The LPH-NP was prepared in a self-assembling process. Briefly, protamine and a mixture of siRNA and hyaluronic acid were mixed to prepare a negat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585496/ https://ncbi.nlm.nih.gov/pubmed/18674578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.07.006 |
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