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Tumor-targeted Delivery of siRNA by Self-assembled Nanoparticles
We have developed a self-assembled nanoparticle (NP) that efficiently delivers small interfering RNA (siRNA) to the tumor by intravenous (IV) administration. The NP was obtained by mixing carrier DNA, siRNA, protamine, and lipids, followed by post-modification with polyethylene glycol and a ligand,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739987/ https://ncbi.nlm.nih.gov/pubmed/17923843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300323 |
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