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Efficient Gene Silencing in Metastatic Tumor by siRNA Formulated in Surface-modified Nanoparticles
We have developed a nanoparticle (NP) formulation for systemically delivering siRNA into metastatic tumors. The NP, composed of nucleic acids, a polycationic peptide and cationic liposome, was prepared in a self-assembling process. The NP was then modified by PEG-lipid containing a targeting ligand,...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692667/ https://ncbi.nlm.nih.gov/pubmed/18083264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.11.002 |
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