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Efficient Gene Silencing in Metastatic Tumor by siRNA Formulated in Surface-modified Nanoparticles
We have developed a nanoparticle (NP) formulation for systemically delivering siRNA into metastatic tumors. The NP, composed of nucleic acids, a polycationic peptide and cationic liposome, was prepared in a self-assembling process. The NP was then modified by PEG-lipid containing a targeting ligand,...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692667/ https://ncbi.nlm.nih.gov/pubmed/18083264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.11.002 |
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