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Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors
Therapies based on RNA interference, using agents such as siRNA, are limited by the absence of safe, efficient vehicles for targeted delivery in vivo. The barriers to siRNA delivery are well known and can be individually overcome by addition of functional modules, such as conjugation of moieties for...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4204797/ https://ncbi.nlm.nih.gov/pubmed/22014944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.09.061 |
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