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Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors

Therapies based on RNA interference, using agents such as siRNA, are limited by the absence of safe, efficient vehicles for targeted delivery in vivo. The barriers to siRNA delivery are well known and can be individually overcome by addition of functional modules, such as conjugation of moieties for...

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Detalhes bibliográficos
Main Authors: Zhou, Jiangbing, Patel, Toral R., Fu, Michael, Bertram, James P., Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204797/
https://ncbi.nlm.nih.gov/pubmed/22014944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.09.061
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