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Tumor-targeted pH/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery
A unique pH/redox dual-sensitive cationic unimolecular nanoparticle (NP) enabling excellent endosomal/lysosomal escape and efficient siRNA decomplexation inside the target cells was developed for tumor-targeted delivery of siRNA. siRNA was complexed into the cationic core of the unimolecular NP thro...
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| Veröffentlicht in: | J Control Release |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538929/ https://ncbi.nlm.nih.gov/pubmed/28159516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.01.042 |
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