Llwytho...

Development of a New Pharmacophore Model that Discriminates Active Compstatin Analogs

Compstatin and its active peptide analogs can potentially be used for therapeutic purposes because their binding to C3 prohibits its conversion into C3b, thus inhibiting complement cascades in all three complement pathways. Mallik and Morikis built three quasi-dynamic pharmacophore models for compst...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chiu, Ting-Lan, Mulakala, Chandrika, Lambris, John D., Kaznessis, Yiannis N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585052/
https://ncbi.nlm.nih.gov/pubmed/18844671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2008.00709.x
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