Evidence for Pore Formation in Host Cell Membranes by ESX-1-Secreted ESAT-6 and Its Role in Mycobacterium marinum Escape from the Vacuole

The ESX-1 secretion system plays a critical role in the virulence of M. tuberculosis and M. marinum, but the precise molecular and cellular mechanisms are not clearly defined. Virulent M. marinum is able to escape from the Mycobacterium-containing vacuole (MCV) into the host cell cytosol, polymerize...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Smith, Jennifer, Manoranjan, Joanna, Pan, Miao, Bohsali, Amro, Xu, Junjie, Liu, Jun, McDonald, Kent L., Szyk, Agnieszka, LaRonde-LeBlanc, Nicole, Gao, Lian-Yong
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2008
Θέματα:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583575/
https://ncbi.nlm.nih.gov/pubmed/18852239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00614-08
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