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The Tec family kinase Itk differentially controls mast cell responses

The Tec family tyrosine kinase Itk is expressed in T cells and mast cells. Mice lacking Itk exhibit impaired T(H)2 cytokine secretion; however, they have increased circulating serum IgE but exhibit few immunological symptoms of allergic airway responses. We have examined the role of Itk in mast cell...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Iyer, Archana S., August, Avery
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583454/
https://ncbi.nlm.nih.gov/pubmed/18523250
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