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Non-receptor tyrosine kinases ITK and BTK negatively regulate mast cell pro-inflammatory responses to lipopolysaccharide
BACKGROUND: Mast cells are indispensible for LPS-induced septic hypothermia, in which TNF-α plays an essential role to initiate septic responses. ITK and BTK regulate mast cell responses to allergen, but their roles in mast cell responses in LPS-induced sepsis are unclear. OBJECTIVES: We sought to i...
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| Gepubliceerd in: | J Allergy Clin Immunol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5730405/ https://ncbi.nlm.nih.gov/pubmed/26581914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.08.056 |
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