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A novel function for the Tec family tyrosine kinase Itk in activation of β1 integrins by the T-cell receptor
Stimulation of T cells via the CD3–T-cell receptor (TCR) complex results in rapid increases in β1 integrin-mediated adhesion via poorly defined intracellular signaling events. We demonstrate that TCR-mediated activation of β1 integrins requires activation of the Tec family tyrosine kinase Itk and ph...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145515/ https://ncbi.nlm.nih.gov/pubmed/11250890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.6.1232 |
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