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The Tec Family Kinase Itk Exists as a Folded Monomer in Vivo
Tec family tyrosine kinases transduce signals from antigen and other receptors. In particular, Itk plays an important role in T-cell development and activation. Itk has an N-terminal pleckstrin homology domain, a Tec Homology domain with a proline-rich region, SH3 and SH2 domains and a kinase domain...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785618/ https://ncbi.nlm.nih.gov/pubmed/19717557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003129 |
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