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The Tec Family Kinase Itk Exists as a Folded Monomer in Vivo

Tec family tyrosine kinases transduce signals from antigen and other receptors. In particular, Itk plays an important role in T-cell development and activation. Itk has an N-terminal pleckstrin homology domain, a Tec Homology domain with a proline-rich region, SH3 and SH2 domains and a kinase domain...

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Bibliografische gegevens
Hoofdauteurs: Qi, Qian, August, Avery
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785618/
https://ncbi.nlm.nih.gov/pubmed/19717557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003129
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