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Association between the Igk and Igh loci mediated by the 3’ Igk enhancer induces decontraction of the Igh locus in pre-B cells
V(D)J recombination at Igh and Igk loci takes place sequentially during successive stages in B cell development. Using 3-dimensional DNA fluorescence in situ hybridization (FISH), we identified a lineage- and stage-specific interchromosomal association between these two loci which marks the transiti...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583163/ https://ncbi.nlm.nih.gov/pubmed/18297074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1567 |
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