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The Ties that Bind (the Igh Locus)
Immunoglobulin heavy-chain locus V(D)J recombination requires a 3D chromatin organization which permits widely distributed variable (V) gene segments to contact distant diversity (D) and joining (J) gene segments. A recent study has identified key nodes in the locus interactome, paving the way for n...
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Publié dans: | Trends Genet |
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Auteur principal: | |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4842146/ https://ncbi.nlm.nih.gov/pubmed/27012539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2016.03.003 |
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