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A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location
Non-biased V gene usage for V(D)J joining is essential for providing an optimal immune system, but no cis-acting sequence with this function has yet been uncovered. We previously identified Sis, a recombination silencer and heterochromatin targeting element in the Vκ-Jκ intervening sequence of germl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080443/ https://ncbi.nlm.nih.gov/pubmed/21441452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003794 |
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