YY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locus

Conditional knock-out (KO) of Polycomb Group (PcG) protein YY1 results in pro-B cell arrest and reduced immunoglobulin locus contraction needed for distal variable gene rearrangement. The mechanisms that control these crucial functions are unknown. We deleted the 25 amino-acid YY1 REPO domain necess...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pan, Xuan, Papasani, Madhusudhan, Hao, Yi, Calamito, Marco, Wei, Fang, Quinn III, William J, Basu, Arindam, Wang, Junwen, Hodawadekar, Suchita, Zaprazna, Kristina, Liu, Huifei, Shi, Yang, Allman, David, Cancro, Michael, Atchison, Michael L
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630362/
https://ncbi.nlm.nih.gov/pubmed/23531880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.66
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados