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A Developmentally Controlled Competitive STAT5-PU.1 DNA Binding Mechanism Regulates Activity of the Ig κE3’ Enhancer
Stage-specific rearrangement of immunoglobulin heavy and light chain genes poses an enigma because both processes utilize the same recombinational machinery, but the heavy chain locus is accessible at the pro-B cell stage, while the light chain loci become accessible at the pre-B cell stage. Transcr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288515/ https://ncbi.nlm.nih.gov/pubmed/22279106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102239 |
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