Transcription Factor YY1 Can Control AID-mediated Mutagenesis

Activation-induced cytidine deminase (AID) is crucial for controlling the immunoglobulin (Ig) diversification processes of somatic hypermutation (SHM) and class switch recombination (CSR). AID initiates these processes by deamination of cytosine, ultimately resulting in mutations or double strand DN...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Zaprazna, Kristina, Basu, Arindam, Tom, Nikola, Jha, Vibha, Hodawadekar, Suchita, Radova, Lenka, Malcikova, Jitka, Tichy, Boris, Pospisilova, Sarka, Atchison, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884117/
https://ncbi.nlm.nih.gov/pubmed/29080214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747065
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