Transcription Factor YY1 Can Control AID-mediated Mutagenesis

Activation-induced cytidine deminase (AID) is crucial for controlling the immunoglobulin (Ig) diversification processes of somatic hypermutation (SHM) and class switch recombination (CSR). AID initiates these processes by deamination of cytosine, ultimately resulting in mutations or double strand DN...

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Udgivet i:Eur J Immunol
Main Authors: Zaprazna, Kristina, Basu, Arindam, Tom, Nikola, Jha, Vibha, Hodawadekar, Suchita, Radova, Lenka, Malcikova, Jitka, Tichy, Boris, Pospisilova, Sarka, Atchison, Michael L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884117/
https://ncbi.nlm.nih.gov/pubmed/29080214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747065
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