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Vκ gene repertoire and locus contraction are specified by critical DNase I hypersensitive sites within the Vκ-Jκ intervening region()
The processes of Ig gene locus contraction and looping during V(D)J-recombination are essential for creating a diverse antibody repertoire. However, no cis-acting sequence that plays a major role in specifying locus contraction has been uncovered within the Igκ gene locus. Here we demonstrate that a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563863/ https://ncbi.nlm.nih.gov/pubmed/23296705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203127 |
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