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The Igκ Gene Enhancers, E3′ and Ed, Are Essential for Triggering Transcription
The mouse Igκ gene locus has three known transcriptional enhancers: an intronic enhancer (Ei), a 3′ enhancer (E3′), and a further downstream enhancer (Ed). Previous studies on B lymphocytes derived from mutant ES cells have shown that deletion of either Ei or E3′ significantly reduces Igκ gene rearr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059262/ https://ncbi.nlm.nih.gov/pubmed/21076060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002665 |
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