Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL

Serum response factor transcriptional activity is controlled through interactions with regulatory cofactors such as the coactivator MAL/MRTF-A (myocardin-related transcription factor A). MAL is itself regulated in vivo by changes in cellular actin dynamics, which alter its interaction with G-actin....

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Autori principali: Mouilleron, Stephane, Guettler, Sebastian, Langer, Carola A, Treisman, Richard, McDonald, Neil Q
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583105/
https://ncbi.nlm.nih.gov/pubmed/19008859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.235
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