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Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

The transcription factor SRF (serum response factor) recruits two families of coactivators, the MRTFs (myocardin-related transcription factors) and the TCFs (ternary complex factors), to couple gene transcription to growth factor signaling. Here we investigated the role of the SRF network in the imm...

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Hlavní autoři: Esnault, Cyril, Stewart, Aengus, Gualdrini, Francesco, East, Phil, Horswell, Stuart, Matthews, Nik, Treisman, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018493/
https://ncbi.nlm.nih.gov/pubmed/24732378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.239327.114
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