Nuclear transport of the serum response factor coactivator MRTF-A is downregulated at tensional homeostasis

The serum response factor (SRF) coactivator myocardin-related transcription factor A (MAL/MKL1/MRTF-A), the nuclear transport and activity of which is regulated by monomeric actin, has been implicated in tension-based regulation of SRF-mediated transcriptional activity. However, the mechanisms invol...

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Detalhes bibliográficos
Main Authors: McGee, Karen M, Vartiainen, Maria K, Khaw, Peng T, Treisman, Richard, Bailly, Maryse
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166461/
https://ncbi.nlm.nih.gov/pubmed/21799516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.141
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