Chargement en cours...

RPEL family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability

RPEL proteins, which contain the G-actin binding RPEL motif, coordinate cytoskeletal processes with actin dynamics. We show that the ArhGAP12- and ArhGAP32-family GTPase activating proteins are RPEL proteins. We determine the structure of the ArhGAP12/G-actin complex, and show that G-actin contacts...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Cell Biol
Auteurs principaux: Diring, Jessica, Mouilleron, Stephane, McDonald, Neil Q., Treisman, Richard
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960015/
https://ncbi.nlm.nih.gov/pubmed/31209295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0337-y
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!