Cdc42 and p190RhoGAP activation by CCN2 regulates cell spreading and polarity and induces actin disassembly in migrating keratinocytes

Cell migration requires spatiotemporal integration of signals that regulate cytoskeletal dynamics. In response to a migration‐promoting agent, cells begin to polarise and extend protrusions in the direction of migration. These cytoskeletal rearrangements are orchestrated by a variety of proteins, in...

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Dettagli Bibliografici
Pubblicato in:Int Wound J
Autori principali: Kiwanuka, Elizabeth, Lee, Cameron CY, Hackl, Florian, Caterson, Edward J, Junker, Johan PE, Gerdin, Bengt, Eriksson, Elof
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949537/
https://ncbi.nlm.nih.gov/pubmed/25185742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iwj.12315
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