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Cdc42 and p190RhoGAP activation by CCN2 regulates cell spreading and polarity and induces actin disassembly in migrating keratinocytes

Cell migration requires spatiotemporal integration of signals that regulate cytoskeletal dynamics. In response to a migration‐promoting agent, cells begin to polarise and extend protrusions in the direction of migration. These cytoskeletal rearrangements are orchestrated by a variety of proteins, in...

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Detalles Bibliográficos
Publicado en:Int Wound J
Main Authors: Kiwanuka, Elizabeth, Lee, Cameron CY, Hackl, Florian, Caterson, Edward J, Junker, Johan PE, Gerdin, Bengt, Eriksson, Elof
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949537/
https://ncbi.nlm.nih.gov/pubmed/25185742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iwj.12315
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