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Coordination of Rho and Rac GTPase function via p190B RhoGAP
The Rac GTPase regulates Rho signaling in a broad range of physiological settings and in oncogenic transformation [1–3]. Here, we report a novel mechanism by which cross-talk between Rac and Rho GTPases is achieved. Activated Rac1 binds directly to p190B RhoGAP (GTPase activating protein), a major m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084715/ https://ncbi.nlm.nih.gov/pubmed/18948007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.09.019 |
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