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Deletion of the P5abc Peripheral Element Accelerates Early and Late Folding Steps of the Tetrahymena Group I Ribozyme

The P5abc peripheral element stabilizes the Tetrahymena group I ribozyme and enhances its catalytic activity. Despite its beneficial effects on the native structure, prior studies have shown that early formation of P5abc structure during folding can slow later folding steps. Here we use a P5abc-dele...

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Autors principals: Russell, Rick, Tijerina, Pilar, Chadee, Amanda B., Bhaskaran, Hari
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582984/
https://ncbi.nlm.nih.gov/pubmed/17419589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0620149
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