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Deletion of the P5abc Peripheral Element Accelerates Early and Late Folding Steps of the Tetrahymena Group I Ribozyme

The P5abc peripheral element stabilizes the Tetrahymena group I ribozyme and enhances its catalytic activity. Despite its beneficial effects on the native structure, prior studies have shown that early formation of P5abc structure during folding can slow later folding steps. Here we use a P5abc-dele...

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Bibliografiske detaljer
Main Authors: Russell, Rick, Tijerina, Pilar, Chadee, Amanda B., Bhaskaran, Hari
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582984/
https://ncbi.nlm.nih.gov/pubmed/17419589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0620149
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