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Deletion of the P5abc Peripheral Element Accelerates Early and Late Folding Steps of the Tetrahymena Group I Ribozyme

The P5abc peripheral element stabilizes the Tetrahymena group I ribozyme and enhances its catalytic activity. Despite its beneficial effects on the native structure, prior studies have shown that early formation of P5abc structure during folding can slow later folding steps. Here we use a P5abc-dele...

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書誌詳細
主要な著者: Russell, Rick, Tijerina, Pilar, Chadee, Amanda B., Bhaskaran, Hari
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582984/
https://ncbi.nlm.nih.gov/pubmed/17419589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0620149
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