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Biomolecular Engineering by Combinatorial Design and High-throughput Screening: Small, Soluble Peptides that Permeabilize Membranes

Rational design and engineering of membrane active peptides remains a largely unsatisfied goal. We have hypothesized that this us due, in part, to the fact that some membrane activities, such as permeabilization, are not dependent on specific amino acid sequences or specific three-dimensional peptid...

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Autors principals: Rathinakumar, Ramesh, Wimley, William C.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582735/
https://ncbi.nlm.nih.gov/pubmed/18611015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8017863
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