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Spontaneous Membrane-Translocating Peptides by Orthogonal High-throughput Screening

Combinatorial peptide chemistry and orthogonal high-throughput screening were used to select peptides that spontaneously translocate across synthetic lipid bilayer membranes without permeabilization. A conserved sequence motif was identified that contains several cationic residues in conserved posit...

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Autores principales: Marks, Jessica R., Placone, Jesse, Hristova, Kalina, Wimley, William C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118567/
https://ncbi.nlm.nih.gov/pubmed/21545169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2017416
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