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The P. furiosus Mre11/Rad50 complex promotes 5’ strand resection at a DNA double-strand break
The Mre11/Rad50 complex has been implicated in the early steps of DNA double-strand break (DSB) repair through homologous recombination in several organisms. However, the enzymatic properties of this complex are incompatible with the generation of 3’ single-stranded DNA for recombinase loading and s...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581932/ https://ncbi.nlm.nih.gov/pubmed/18957200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.09.054 |
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