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Mre11–Rad50–Xrs2 and Sae2 promote 5’ strand resection of DNA double-strand breaks
The repair of DNA double-strand breaks by homologous recombination is essential for genomic stability. The first step in this process is resection of 5’ strands to generate 3’ single-stranded DNA intermediates. Efficient resection in budding yeast requires the Mre11–Rad50–Xrs2 (MRX) complex and the...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059534/ https://ncbi.nlm.nih.gov/pubmed/21102445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1957 |
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