Llwytho...

Mre11–Rad50–Xrs2 and Sae2 promote 5’ strand resection of DNA double-strand breaks

The repair of DNA double-strand breaks by homologous recombination is essential for genomic stability. The first step in this process is resection of 5’ strands to generate 3’ single-stranded DNA intermediates. Efficient resection in budding yeast requires the Mre11–Rad50–Xrs2 (MRX) complex and the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nicolette, Matthew L., Lee, Kihoon, Guo, Zhi, Rani, Mridula, Chow, Julia M., Lee, Sang Eun, Paull, Tanya T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059534/
https://ncbi.nlm.nih.gov/pubmed/21102445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1957
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