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The P. furiosus Mre11/Rad50 complex promotes 5’ strand resection at a DNA double-strand break

The Mre11/Rad50 complex has been implicated in the early steps of DNA double-strand break (DSB) repair through homologous recombination in several organisms. However, the enzymatic properties of this complex are incompatible with the generation of 3’ single-stranded DNA for recombinase loading and s...

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Detalhes bibliográficos
Main Authors: Hopkins, Ben B., Paull, Tanya T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581932/
https://ncbi.nlm.nih.gov/pubmed/18957200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.09.054
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