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Making the Best of the Loose Ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection

Double-strand breaks in chromosomal DNA are repaired efficiently in eukaryotic cells through pathways that involve direct religation of broken ends, or through pathways that utilize an unbroken, homologous DNA molecule as a template for replication. Pathways of repair that require homology initiate...

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Bibliographic Details
Main Author: Paull, Tanya T.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004398/
https://ncbi.nlm.nih.gov/pubmed/21050828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.09.015
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