Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks

Single-stranded DNA constitutes an important early intermediate for homologous recombination and damage-induced cell cycle checkpoint activation. In Saccharomyces cerevisiae, efficient double-strand break (DSB) end resection requires several enzymes; Mre11/Rad50/Xrs2 (MRX) and Sae2 are implicated in...

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Main Authors: Shim, Eun Yong, Chung, Woo-Hyun, Nicolette, Matthew L, Zhang, Yu, Davis, Melody, Zhu, Zhu, Paull, Tanya T, Ira, Grzegorz, Lee, Sang Eun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957216/
https://ncbi.nlm.nih.gov/pubmed/20834227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.219
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