The Antiherpetic Drug Acyclovir Inhibits HIV Replication and Selects the V75I Reverse Transcriptase Multidrug Resistance Mutation

The antiviral drug acyclovir is a guanosine nucleoside analog that potently inhibits herpes simplex virus (HSV) replication. Acyclovir treatment in patients coinfected with HSV and human immunodeficiency virus (HIV) has been observed to alter disease course and decrease HIV viral load, a finding tha...

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Detalhes bibliográficos
Main Authors: McMahon, Moira A., Siliciano, Janet D., Lai, Jun, Liu, Jun O., Stivers, James T., Siliciano, Robert F., Kohli, Rahul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Accelerated Publications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581555/
https://ncbi.nlm.nih.gov/pubmed/18818198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800188200
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