The Antiherpetic Drug Acyclovir Inhibits HIV Replication and Selects the V75I Reverse Transcriptase Multidrug Resistance Mutation

The antiviral drug acyclovir is a guanosine nucleoside analog that potently inhibits herpes simplex virus (HSV) replication. Acyclovir treatment in patients coinfected with HSV and human immunodeficiency virus (HIV) has been observed to alter disease course and decrease HIV viral load, a finding tha...

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Bibliografiske detaljer
Main Authors: McMahon, Moira A., Siliciano, Janet D., Lai, Jun, Liu, Jun O., Stivers, James T., Siliciano, Robert F., Kohli, Rahul M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Accelerated Publications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581555/
https://ncbi.nlm.nih.gov/pubmed/18818198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800188200
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