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The Kinetics of Anesthetic-induced Conformational Transitions in a Four-α-Helix Bundle Protein
Inhaled anesthetics are thought to alter the conformational states of Cys-loop ligand-gated ion channels (LGICs) by binding within discrete cavities that are lined by portions of four α-helical transmembrane domains. Because Cys-loop LGICs are complex molecules that are notoriously difficult to expr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581500/ https://ncbi.nlm.nih.gov/pubmed/16445285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052206o |
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