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Inhibition of Human α(4)β(2) Neuronal Nicotinic Acetylcholine Receptors by Volatile Aromatic Anesthetics Depends on Drug Hydrophobicity

BACKGROUND: Volatile aromatic compounds such as benzene are general anesthetics that cause amnesia, hypnosis, and immobility in response to noxious stimuli when inhaled. Although these compounds are not used clinically, they are frequently found in commercial items such as solvents and household cle...

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Detalhes bibliográficos
Main Authors: Solt, Ken, Kelly, Elizabeth W., Cotten, Joseph F., Raines, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534757/
https://ncbi.nlm.nih.gov/pubmed/19917625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3181c5f689
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