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SAR by Oxime-Containing Peptide Libraries: Application to Tsg101 Ligand Optimization
HIV-1 viral assembly requires a direct interaction between a Pro-Thr-Ala-Pro (“PTAP”) motif in the viral protein Gag-p6 and the cellular endosomal sorting factor Tsg101. In an effort to develop competitive inhibitors of this interaction, an SAR study was conducted based on the application of post so...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581409/ https://ncbi.nlm.nih.gov/pubmed/18655064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800281 |
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